Non-Canonical MYD88/TIRAP-Dependent Anti-Inflammatory Function of Pro-Coagulant Factor VIII
نویسندگان
چکیده
منابع مشابه
Anti-inflammatory, anti-coagulant, anti-biotic?
2013; 109: 684-695. Systemic activation of inflammatory cascades and coagulation are a hallmark in the pathogenicity of infectious diseases that significantly contribute to morbidity and mortality of severely infected patients. Complications are often evoked by an overreaction of host defense systems to the infection and thus many antimicrobial drugs have been developed that have anti-inflammat...
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Factor VIII coagulant activity (VIII(C)) and the von Willebrand's disease antigen (Factor VIII-like antigen, vW-Ag) are biologically linked, and it has been suggested that they reside on the same molecule. However, insolubilized human isoantibody to VIII(C) and rabbit antiserum containing antibodies to VIII(C) and vW-Ag differentially bind and remove these entities from plasma, thus physically ...
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ژورنال
عنوان ژورنال: Blood
سال: 2019
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2019-127504